Media Release 05 Oct 2007

NSH and Northern Clinical School Research Winners

Royal North Shore Hospital and the Northern Clinical School of the University of Sydney, have together successfully secured more than $5.25 million from the National Health and Medical Research Council (NHMRC) to fund 15 individual research projects this year.

Royal North Shore Hospital (RNSH) is a research-based hospital that aims to take good ideas, as we say, ‘from bench top to bedside. It is one of the leading medical and research hospitals in NSW and works closely with the University of Sydney, University of Technology, Sydney and other hospitals and universities, pharmaceutical companies and industry groups to improve the care of patients across NSW, throughout Australia and, in some cases, worldwide.
The Kolling Institute of Medical Research is the oldest medical research institute in New South Wales. Senior scientists and clinicians guide the work of over 100 PhD students on the RNSH campus

RNSH significantly out performed the national average (27.9%) with a 36% success rate.

Congratulations to:

Dr Mark Connor, Pain Management Research Institute
Effects of muscle inflammation on sensory neuron excitability $408,500

Dr Christine Roberts, Obstetrics and Gynaecology
Identifying risk for second and subsequent pregnancies: a longitudinal record linkage study $564,000

Dr James Melrose, Raymond Purves Bone & Joint Research Labs
The role of perlacan in tensional connective tissues $580,500

Dr Jonathon Morris, Obstetrics & Gynaecology
Understanding immune tolerance in pregnancy to discover a new intervention for the treatment of pre-eclampsia $472,350

Dr Nghia Le, Sutton Arthritis Research Laboratory
The Molecular Biology of Synoviocyte Invasion in Tendon of Patients with Rheumatoid Arthritis $107,750

Professor Carol Pollock, Renal Medicine
TGFbeta isoforms differentially regulate fibrosis and inflammation in diabetic nephropathy via KLF transcription factors $518,750

Dr Carolyn Scott, Kolling Institute
The role of the M6P/IGF-11 receptor in regulating cellular function $265,500

Dr Chris Jackson, Sutton Arthritis Research Laboratory
Activated protein C utilises protease activated receptors and epidermal growth factor receptor to heal wounds $228,750

Professor Mac Christie, Pain Management Research Institute
Role of GAT-1 transporter channels in opioid dependence $503,250

A/Professor Chris O'Neill, Human Reproduction Unit
The role of transcription factors in regulating the first round of gene expression in the early embryo $334,875
Mechanisms of p53 induced embryopathy after in vitro fertilisation $464,250

A/Professor Janet Keast, Pain Management Research Institute
Plasticity and regeneration of bladder, motor nerve circuits after injury $319,875

Dr Hugh Morgan, Human Reproduction Unit
Characterisation of the pathways leading to DNA demethylation in the embryo. $608,865

Dr Anthony Ashton, Kolling Institute
Thromboxane receptor signalling in endothelial cells $553,750

Prof Philip Sambrook, Rheumatology Common pathways influencing osteoporosis and atherosclerosis clinical risk $426,107

Work is currently underway for the New Research & Education Building at RNS which will give medical research and clinical teaching a strong, recognisable identity by gathering together the groups that are currently scattered across the campus into an ultra-modern purpose-built facility. The building is due for completion in late 2008.

Media Contact: Penelope Little 9926 7199 / 0413 025 742

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